Publications

Anti-TB drug concentrations and drug-associated toxicities among TB/HIV-coinfected patients

  • Articles
  • Published in Journal of Antimicrobial Chemotherapy on January 19, 2017

Abstract Background: Toxicities due to anti-TB treatment frequently occur among TB/HIV-coinfected patients. Objectives: To determine the association between anti-TB drug concentrations and the occurrence of hepato- toxicity and peripheral neuropathy among TB/HIV-coinfected patients. Methods:...

Early virological failure and HIV drug resistance in Ugandan adults co-infected with tuberculosis

  • Articles
  • Published in AIDS Research and Therapy on January 05, 2017

Abstract Background: This cross-sectional study took place in the integrated tuberculosis (TB) clinic of a large outpatient clinic for HIV-infected patients in Kampala, Uganda. The purpose of this study was to describe the proportion...

Challenges in achieving a target international normalized ratio for deep vein thrombosis among HIV-infected patients with tuberculosis: a case series

  • Articles
  • Published in BMC Hematology on June 04, 2016

Abstract Background: Tuberculosis (TB) and HIV are among the risk factors for deep vein thrombosis (DVT). There are several challenges in the management of DVT patients with TB-HIV co-infection including drug-drug interactions and non-adherence...

Low prevalence of pre-treatment HIV-1 drug resistance in Ugandan adults

  • Abstracts
  • Presented at HIV Drug Therapy Glasgow, Scotland (23-26 October 2016)

Authors: Amrei von Braun (1,2), Christine Sekaggya (1), Alexandra Scherrer (2,3), Brian Magambo (4), Deogratius Ssemwanga (4), Pontiano Kaleebu (4), Huldrych Günthard (2,3), Andrew Kambugu (1), Jan Fehr (2), Barbara Castelnuovo (1) Affiliations: Infectious...

High rates of multi class drug resistance in HIV-1 infected individuals monitored with CD4 count in Uganda

  • Abstracts
  • Presented at HIV Drug Therapy Glasgow, Scotland (23-26 October 2016)

Authors: Amrei von Braun (1,2), Alexandra Scherrer (2,3), Christine Sekaggya (1), Joseph Kirangwa (4), Deogratius Ssemwanga (4), Pontiano Kaleebu (4), Huldrych Günthard (2,3), Andrew Kambugu (1), Barbara Castelnuovo (1), Jan Fehr (2) Affiliations: Infectious...

Low rifampicin and isoniazid concentrations are associated with delayed sputum conversion in HIV positive patients co-infected with tuberculosis in Uganda.

  • Abstracts
  • Presented at HIV Drug Therapy Glasgow, Scotland (23-26 October 2016)

Authors: Christine Sekaggya-Wiltshire(1),  Bruno Ledergerber(2), Amrei von Braun(1,2), Mohammed Lamorde(1), Allan Buzibye(1), Nadia Eberhard(1,2), Alexandra Scherrer (2), Rita Nakijoba(1), Daniel Muller(3), Lars Henning(2), Ursula Gutteck (3), Natascia Corti(4), Joseph Musaazi(1), Moses Kamya(5), Barbara Castelnuovo(1),...

“If at first you don’t succeed, try again”: Looking beyond Initial Results of a Failed Tuberculosis Diagnosis

  • Articles
  • Published in Public Health Action on September 21, 2015

Abstract: We report the outcome of investigations conducted in 73 human immunodeficiency virus (HIV) infected Ugandan adults presumed to have pulmonary tuberculosis (PTB). Following initial investigations, 32 of 73 patients were diagnosed with PTB....

Low isoniazid and rifampicin concentrations in TB/HIV co-infected patients in Uganda

  • Abstracts
  • Presented at HIV Drug Therapy Glasgow (2-6 November 2014)

Authors: Sekaggya C (1), Lamorde M (1), Scherrer A.U (2), Musaazi J (1), Corti N (2), Buzibye A (1), Nakijoba R (1), Nalwanga D (1), Henning L (2), von Braun A (1), Okware S...

Association of anti-tuberculosis drug levels serum concentrations with drug-related adverse events in TB/HIV co-infected patients in Uganda

  • Abstracts
  • Presented at European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) (25-28 April 2015)

Authors: C. Sekaggya (1), A. von Braun (1), B. Ledergerber (2), A. Buzibye (1), A. Scherrer (2), M. Lamorde M, D. Nalwanga (1), L. Henning (2), D. Muller (2),U. Gutteck (2), B. Castelnuovo (1),...

Importance of continuous monitoring of HIV-infected patients screened for pulmonary tuberculosis – independently of screening results

  • Abstracts
  • Presented at European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) (25-28 April 2015)

Authors: A. von Braun(1), C. Sekaggya(1), L. Henning(2), R. Nakijoba(1), I. Ariko(1),  J. Mayito(1), D. Nalwanga(1), S. Okware(1), B. Castelnuovo(1), J. Fehr (2), A. Kambugu(1) 1) Infectious Diseases Institute, College of Health Sciences, Makerere...