Bruno Ledergerber has a background in electronic engineering and computer science with further specialization in clinical epidemiology and medical informatics. From 1987-1988 he has set up the database for the Swiss HIV Cohort Study (SHCS) and headed its data and coordinating center from 1988-1995. Since then he has performed numerous analyses on the SHCS database and initiated/analyzed several international cohort projects. Together with Alexandra Scherrer he is supporting R4GH with regards to challenges in data management and statistics.